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2022 MLB playoffs: Mets vs. Padres odds, line, Wild Card Series Game 1 picks, predictions by proven model

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The 2022 MLB playoffs get rolling on Friday and the New York Mets (101-61) are set to host the San Diego Padres (89-73) for Game 1 of their Wild Card Series in the final matchup of the day. New York saw a 10.5-game lead in the NL East disappear as the Atlanta Braves took the division in the final week of the regular season. San Diego, meanwhile, finished 22 games behind the Dodgers in the NL West, but the Padres claimed the second wild-card spot ahead of the Phillies. Max Scherzer (11-5, 2.29 ERA) will start for New York while the Padres will counter with Yu Darvish (16-8, 3.10 ERA).

First pitch is at 8:07 p.m. ET. Caesars Sportsbook lists New York as the -155 favorite (risk $155 to win $100) on the money line in the latest Mets vs. Padres odds. San Diego is the +130 underdog and the over/under for total runs scored is set at 6. Before making any Padres vs. Mets picks, you need to see the MLB predictions and betting advice from SportsLine’s advanced computer model.

The SportsLine Projection Model simulates every MLB game 10,000 times, and it entered the final week of the regular season on an 18-8 run on top-rated money-line MLB picks, returning almost $700 for $100 players. This is the same model that pegged the 2021 Atlanta Braves at 10-1 as one of three best bets to win it all last season. Anybody who has followed it has seen huge returns.

Now, the model has set its sights on Mets vs. Padres, and just locked in its picks and MLB predictions. You can head to SportsLine now to see the model’s picks. Here are several MLB odds and betting lines for Padres vs. Mets:

  • Mets vs. Padres money line: New York -155, San Diego +130 
  • Mets vs. Padres over/under: 6 runs 
  • Mets vs. Padres run line: New York -1.5 (+162)
  • NYM: The Mets have lost five of their last six postseason games 
  • SD: The Padres are 1-5 in their last six road playoff contests 
  • Mets vs. Padres picks: See picks here

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