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Astros vs. White Sox odds, prediction, line, time: 2023 MLB picks, Saturday, April 1 bets from proven model

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Teams looking to get a leg up in their season-opening series meet in Game 3 of their four-game series on Saturday when the Chicago White Sox battle the Houston Astros. The White Sox (1-1), who missed the playoffs a year ago, are looking to rebound this year and return to the postseason for the third time in four years. The Astros (1-1), who have reached the playoffs in each of the past six seasons, have won two World Series during that span and finished runner-up twice. Houston won four of the seven meetings with Chicago last year. Jose Urquidy will be on the hill for Houston, while Lucas Giolito is starting for Chicago. 

The game is slated to begin at 2:10 p.m. ET from Minute Maid Park in Houston. The White Sox hit .256 as a team last year, fifth-best in MLB, while the Astros had a .248 average, 12th-best. Houston is the -125 favorite (risk $125 to win $100) on the money line in the latest White Sox vs. Astros odds from Caesars Sportsbook, while the over/under for total runs scored is 8.5. Before making any Astros vs. White Sox picks, be sure to check out the latest MLB predictions and betting advice from the SportsLine Projection Model.

The SportsLine Projection Model simulates every MLB game 10,000 times. It went 331-285 on top-rated MLB money-line picks (+357) over the past two seasons, and it finished the 2022 MLB season on a 20-14 roll. Anybody who has followed it has seen profitable returns.

Now, the model has dialed in on White Sox vs. Astros and revealed its predictions and best bets. You can visit SportsLine now to see the model’s MLB picks. Here are the MLB odds and betting trends for Astros vs. White Sox:

  • White Sox vs. Astros money line: Chicago +105, Houston -125
  • White Sox vs. Astros over/under: 8.5 runs
  • White Sox vs. Astros run line: Astros -1.5 (+158)
  • CWS: The White Sox are 5-2 in their last five games against American League West opponents
  • HOU: The Astros are 6-0 in their last six Saturday games
  • White Sox vs. Astros picks: See picks at SportsLine

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